E50 Exosomes for Hair

Exosomes are small extracellular vesicles secreted by various cell types. These tiny structures play a pivotal role in cell-to-cell communication. They contain bioactive molecules like proteins, lipids and genetic material, which can influence the behaviour of recipient cells. In aesthetic medicine, exosomes are being studied for potential roles in regenerative care, making them a promising area of research for skin and hair loss.

These vesicles may be formulated with selected signalling molecules (such as growth factors and cytokines). When applied to the scalp, the intention is to support the scalp and follicle environment; clinical evidence is still developing and outcomes vary. Exosomes can be discussed alongside our other hair-loss management options at Bioscor, as part of a combination-therapy approach under medical supervision; suitability and responses vary. As an emerging therapeutic solution, exosome-based care reflects ongoing technological advancement in the development of regenerative hair restoration.

Why E50 Exosomes for Hair Loss?

E50 Exosomes are derived from marine sources, using EVSTA (Extracellular Vesicle Standardized Testing Architecture) processes. Through defined cultivation and preservation methods, E50 Exosomes are prepared to maintain product quality. In aesthetic medicine, exosomes are being studied for potential roles in skin and hair biology; clinical evidence is still developing and outcomes vary. This biologically derived technology supports targeted cellular signalling within the scalp environment, aligning with current approaches in regenerative medicine and tissue repair.

E50 Exosomes are rich in essential components that drive their regenerative capabilities:

  • Growth Factors – promote cellular proliferation and tissue repair.
  • MiRNAs – act as signals to induce specific cellular pathways associated with cellular regeneration.
  • Cytokines – modulate the immune response and reduce inflammation.
  • Proteins and Lipids – essential for cellular communication and structural integrity.

Together, these biologically active components contribute to the advancement of regenerative strategies in hair restoration by supporting cellular communication, repair, and growth pathways.

exosome therapy procedure
E50-Hair

Benefits of E50 Exosomes

E50-H is an advanced exosome treatment for hair designed to enhance cellular activity within the hair follicle ecosystem. It promotes the proliferation and differentiation of crucial cells, including hair follicle stem cells, outer root sheath cells, and dermal papilla cells. E50-H plays a pivotal role in regulating the hair growth cycle by stimulating the transition from the dormant telogen (resting) phase to the active anagen (growth) phase, while also delaying the onset of the catagen (transition) phase. Additionally, E50-H promotes angiogenesis, facilitating the formation of new blood vessels, and reduces inflammation, making it potentially beneficial for individuals with scalp conditions such as psoriasis, seborrheic dermatitis, and other inflammatory scalp disorders. These mechanisms may complement other hair restoration strategies by enhancing the scalp microenvironment and modulating inflammatory responses that can contribute to certain types of hair loss.

Applied using TargetCool

At Bioscor, we utilise TargetCool to apply the E50 Exosomes to the scalp, providing an effective method for delivering active ingredients directly to the dermal-epidermal junction (DEJ). This targeted delivery aims to stimulate the dermal papilla cells, which are essential in regulating hair follicle growth and cycling. This hair loss treatment in Melbourne is non-invasive, with the Boosting Mode ensuring completely pain-free transdermal delivery. Additionally, the application of CO2 offers anti-inflammatory benefits. Specifically designed to work with E50-H Exosomes, the TargetCool device ensures these bioactive contents are preserved and delivered deep into the DEJ layer for maximum results. This targeted delivery approach reflects current innovation in transdermal therapeutic technology, aiming to optimise the precision and efficacy of regenerative treatments for hair loss.

TargetCool

Results

Some people report changes gradually over several months as part of ongoing care; outcomes and timeframes vary. This case example shows one patient’s experience following one exosome session at our Melbourne clinic. It is illustrative only and not predictive of individual outcomes.

Patient has given consent for the use of his photo. Patient results may vary. While individual results vary, the exploration of exosome-based therapies marks a promising advancement in the research and development of regenerative approaches to hair restoration.

Exosomes for Hair - Bioscor InternationalExosomes for Hair - Bioscor International
Exosomes for Hair - Bioscor InternationalExosomes for Hair - Bioscor International

FAQs

Exosome therapy has burst onto the market, with a growing number of companies offering exosome products. We conducted an extensive amount of market research to choose the right exosome product for us. E50 exosomes is the logical choice for us based on three main criteria: stability, purity and source. These qualities contribute to greater consistency in formulation and delivery, supporting the potential for more reproducible outcomes in regenerative applications.

Lyophilisation (also known as freeze-drying, is a process used to preserve biological materials) is the preferred method for preserving exosomes, as it stabilises them and prevents denaturation (when a protein loses its normal shape and function due to changes in conditions) over time. While pre-suspended exosomes claim long shelf lives at ambient temperatures, lyophilised exosomes are considered the “Gold Standard” for ensuring stability, similar to how other products like botulinum toxin are preserved. E50 stands out by using hyaluronic acid in its lyophilisation process, further enhancing exosome preservation and effectiveness, compared to the more common mannitol or sucrose methods. This enhanced stability facilitates reliable storage and application, supporting the broader development and clinical viability of next-generation exosome therapies.

Exosome products often contain a mix of exosomes, cellular debris, and apoptotic bodies (dead cells), which can reduce the effectiveness and increase the risk of adverse reactions. Many companies count particles within a certain size range, rather than specifically counting exosomes, leading to a higher chance of impurities in the final product.

PrimaCure, the manufacturer of E50, addresses this challenge by using a patented ultrasound technique that not only boosts the production of exosomes but also selectively enriches them with the desired proteins necessary for skin and hair health. The ultrasound process causes cells to release more exosomes while also helping to reduce the presence of unwanted impurities, such as cellular debris and apoptotic bodies. By fine-tuning the conditions during exosome production and ensuring that only the most relevant bioactive components are included, E50 offers a purer, more effective exosome product. This means a higher concentration of beneficial exosomes and a lower risk of complications.

The choice of salmon testis cells addresses safety concerns associated with other cell types (e.g. human-derived) raised by various regulatory bodies, due to a combination of ethical and theoretical safety concerns. In contrast, salmon is a safe choice because diseases and viruses typically cannot transmit from fish to humans. Furthermore, plant-derived exosomes are ineffective due to the fundamental differences in cellular membrane structures between plants and humans.

The use of salmon genetic materials in regenerative medicine is well-documented and has been a cornerstone of the polynucleotide industry for over three decades. Outside of aesthetics, salmon-derived genetic materials have demonstrated the ability to induce cellular pathways critical for regeneration and repair.

This specific sourcing approach also opens avenues for future research into marine-derived regenerative compounds, particularly where safety, scalability, and immunogenicity are key considerations in clinical and aesthetic applications.

SPECIAL – limited time only!

1 Session – $450 $300

2 Session Pack – $800 $500 ($250 per session)

The typical treatment protocol for E50-H involves five sessions, with two treatments in the first month, followed by monthly sessions. After this initial course, maintenance treatments every two to six months are recommended depending on your needs. This staged development approach aligns with the natural timeline of hair growth cycles and targeted regenerative healing.

Discomfort during the procedure is minimal. Some patients may experience mild discomfort or a slight stinging sensation during the micro-needling process. The latter process involving administration via the TargetCool device is pain-free. Although your scalp may feel slightly sensitive after the treatment, it is usually safe to resume your day as per normal.

  • Individuals who are pregnant and/or breastfeeding.
  • History of cancer or autoimmune disease.
  • History of severe allergic reactions.
  • Active infections or inflammation.
  • Bleeding disorders or anticoagulant therapy.
  • Individuals who are on immunosuppressive therapy.

Before considering E50 exosome therapy for hair loss, it’s crucial to consult with a qualified healthcare provider who can conduct a thorough medical evaluation, discuss potential risks and benefits, and determine if this treatment is appropriate based on individual health conditions and medical history.

It is usually safe to combine this treatment with other treatments you may have been prescribed by our medical practitioner.

At Bioscor, we believe in combination-therapy for maximum results, which is widely regarded as the most effective approach to treating hair loss. Exosomes may complement other therapeutic solutions by enhancing targeted activity, supporting scalp healing, and reinforcing ongoing hair restoration strategies.

This page is only intended to provide factual information to educate individuals who are interested in learning more about the treatment. Our clinic offers a health-practitioner-led consultation. Depending on the outcome of the consultation, this may or may not lead to the provision of a prescription.