What is Rejuran

Rejuran is an advanced injectable skin booster made from high-purity polynucleotides (PNs) — naturally occurring DNA fragments derived from salmon, chosen for their high biocompatibility with human skin. These polynucleotides are suspended in a soft gel matrix designed for injection into the dermal layer, where they may support the skin’s natural structure and hydration environment.

Unlike dermal fillers that aim to add volume, Rejuran’s focus is on skin quality — helping to improve texture, elasticity, and radiance from within. It works by delivering bioactive molecules that are thought to influence the extracellular environment, helping to create a more resilient, supple complexion over time. The treatment has gained popularity across Asia and globally for its use in restoring skin freshness, especially in those experiencing early signs of skin fatigue, loss of firmness, or dullness.

By enhancing the skin’s foundational structure rather than simply adding volume, Rejuran encourages ongoing skin renewal, hydration, and a subtle, natural glow. This non-volumising approach allows individuals to maintain their facial contours while improving overall skin quality.

The procedure is minimally invasive, typically well-tolerated, and performed by a qualified dermatologist or practitioner who carefully injects microdoses into targeted areas of concern.

Rejuran injectables are commonly used in a variety of zones, including the full face for general rejuvenation, the under-eye area where the skin is thinnest, the neck and décolletage prone to environmental damage, and localised areas of skin texture irregularity such as acne scars.

Over the weeks following treatment, many clients notice subtle improvements in texture, elasticity, and radiance, resulting from the combined effects of collagen stimulation, dermal repair, and ongoing skin regeneration.

By working within the skin rather than on its surface, Rejuran offers a non-volumising option for individuals looking to support their skin’s foundational health and appearance through a regenerative, injectable-based approach.

Rejuran injectables are commonly used in a variety of zones, including:

  • The full face, for general rejuvenation
  • The under-eye area, where the skin is thinnest and most delicate
  • The neck and décolletage, which often show signs of environmental damage
  • Localised areas of skin texture irregularity, such as previous acne scars

Types of Rejuran Injectable Treatments

Each Rejuran formulation is developed with a specific focus and application area in mind. Your practitioner will determine which is most appropriate during your consultation.

Rejuran Classic

  • General-purpose injectable
  • Often used for full-face treatment to support overall skin quality and texture
  • Suitable for individuals seeking skin revitalisation without adding volume

Rejuran i

  • Specifically designed for the delicate under-eye area
  • Lightweight formulation aimed at improving elasticity and hydration in thin, fragile skin
  • Commonly used for individuals with crepiness or mild fine lines under the eyes

Rejuran s

  • Formulated for scarred or textured skin
  • Often used in areas where targeted dermal support is desired
  • Your practitioner may recommend Rejuran s in a spot-treatment protocol depending on your skin’s presentation

Note: While Rejuran products are used to support skin texture and hydration, they are not classified as therapeutic goods for the treatment of skin disease or scarring. Treatment suitability will be assessed individually.

Before and after images provided by the Australian distributor of Rejuran. Individual results vary. Images are unedited and used with permission for educational purposes only. Treatment outcomes depend on individual skin condition, product selection, and practitioner technique.

Before and after images provided by the Australian distributor of Rejuran. Individual results vary. Images are unedited and used with permission for educational purposes only. Treatment outcomes depend on individual skin condition, product selection, and practitioner technique.

Who is it for?

Rejuran injectable treatments may be appropriate for individuals looking to:

  • Enhance skin texture, elasticity, and hydration
  • Support the appearance of fine lines
  • Address dull or tired-looking skin
  • Explore non-volumising injectable options

During your consultation, your practitioner will assess whether Rejuran and which formulation is suitable for your skin and goals.

Potential Benefits of Rejuran

  • Supports natural collagen production for firmer, more youthful-looking skin.
  • Helps promote tissue repair and healing, supporting healthier skin function.
  • Improves overall texture for a smoother, refined complexion.
  • Encourages deep-layer regeneration within the skin’s dermis.
  • Assists in reducing visible early anti-ageing concerns, such as mild laxity or fine lines.
  • Enhances hydration and restores a soft, natural glow.
  • Works beneath the surface to support long-term skin renewal without creating volume.
  • Suitable as a non-volumising option for individuals wanting a subtle, regenerative boost rather than a filler-like effect.

FAQs

Rejuran is not a volumising filler. Instead of adding structure or lift, it works within the skin to support hydration, texture, and elasticity. It’s often chosen by individuals seeking natural-looking skin quality improvements without altering facial contours.

Rejuran is an ARTG-listed Class III medical device and is widely used across aesthetic clinics in Australia and internationally. It is composed of highly purified polynucleotides derived from salmon DNA, which are known for their biocompatibility with human tissue. Like all injectable treatments, it must be administered by a trained practitioner and may involve minor, temporary side effects such as redness, swelling, or small bumps at the injection sites.

Many patients begin with an initial course of 3–4 sessions spaced 2–4 weeks apart, followed by maintenance treatments a few times a year. However, the number and timing of sessions will depend on your skin condition, goals, and the advice of your treating practitioner.

Some patients report improvements in skin texture and hydration within several weeks of treatment, with gradual enhancement over time. As Rejuran is not a filler and does not provide instant volume, outcomes are subtle and cumulative. Individual results vary.

Mild swelling, redness, or small bumps at the injection sites are common and typically resolve within 24 to 72 hours. Some individuals may experience mild bruising. Most patients can resume normal daily activities the same or next day, depending on their comfort level.

Yes, Rejuran is often combined with other in-clinic modalities such as microneedling, LED therapy, or low-volume dermal fillers. Your practitioner can advise on the best combination plan for your skin needs during consultation.

Rejuran may be suitable for individuals seeking subtle, regenerative skin support, especially those with concerns related to texture, fine lines, or overall skin quality. A consultation is required to determine whether Rejuran is appropriate for you, based on your skin condition and medical history.

This page is intended for general educational purposes only. Rejuran products are ARTG-listed medical devices administered under medical supervision. Individual suitability, outcomes and treatment protocols will be assessed by a registered health practitioner during consultation. No therapeutic claims are made about treating skin disease or medical conditions.